Purpose: This review aims to examine the current knowledge regarding to the molecular mechanisms by several nutraceuticals, such as retinoids, resveratrol, epigallocatechin 3 gallate, and omega-3 PUFAs to against cancer. Bioactive compounds with high contents in nutraceuticals are considered as complementary components in foods, dietary supplements, and medicines. These compounds can also inhibit carcinogenesis, protect body cells from inflammatory and oxidative processes, and induce anti-proliferative effects in various types of neoplasia. Research Methodology: The method used is a literature review. The literature search was conducted through Pubmed using keywords in the 2012-2021 timeframe. Result: The results obtained are that bioactive compounds from nutraceuticals, such as RSV, retinoids, EGCG, and omega-3 PUFAs, have the ability to influence the growth and development of cancer cells, therefore, nutraceuticals can work as innovative anticancer agents. Limitations: By this method, a thorough literature search may miss important studies that influence conclusions. Contribution: This research can be applied by all of cancer patients because nutraceutical ingredients are easily available throughout the world, including Indonesia.  

Purpose: This study aims to review the existing literature regarding dietary interventions for the prevention of obesity in children and their effectiveness. Metode: A literature search was carried out using search engines PubMed Central, Elsevier and Google Scholar, limiting the last 10 years to articles from 2011 to 2021. Result: Most of the programs/interventions carried out focused mainly on school-based intervention approaches, community-based interventions, interventions through mass media and food sector interventions. In its own application, this control is divided into two parts, namely micro and macro policies. Limitation: This article is only a review of several other articles, not doing research directly. Contribution: With proper examination, it is hoped that cases of children’s obesity can be prevented by some dietary interventions.

Purpose: This study aimed to summarize the general history, physical exam findings, confirmation test, and treatment of a patient with rapunzel syndrome. Research Methodology: This article is a pediatric surgery RSUD Abdoel Moeloek Lampung case report in 11 March 2020. The subject of the case is a 11-year-old girl who is hospitalized in the hospital ward with Rapunzel syndrome. Result: A 11-year-old girl, an inpatient in the Pediatric surgery Ward, RSUD Abdoel Moeloek Lampung, with abdominal pain such as squeezing, nausea and vomiting filled with water and hard and little bowel movements.. On physical examination, bloated abdomen, epigastric tenderness and left hypochondrium, mass (+).on ct scan examination with gastric contrast looks enlarged, isodense lesions appear, irregular edges in the gastric lumen to the duodenum, separated from the wall, post contrast does not appear enhanced. The patient was clinically diagnosed with “Rapunzel Syndrome.” Management of the patient during treatment was upper midline laparatomy. Limitations: This case report is limited to rapunzel syndrome cases with a scarce number of cases and rare cases in children. Contribution: This case report can be helpful in medical education or used as a reference in making relevant case reports and can be applied in the hospital area when there are cases of Rapunzel syndrome.