Pengaruh Profil Pasien Kanker yang Mendapat Kemoterapi dengan Chemotherapy Induced Nausea and Vomiting (CINV)

https://doi.org/10.35912/nersakademika.v3i1.3905
Published: Dec 10, 2024

Abstract:

Purpose: This study aimed to examine the effect of cancer patient profiles receiving chemotherapy on Chemotherapy-Induced Nausea and Vomiting (CINV). This study aimed to identify the factors related to the development of CINV in patients with cancer undergoing chemotherapy and to provide a better understanding of how patient characteristics influence their vulnerability to these side effects.

Methods: This was a quantitative study with a correlation study design. The sample size consisted of 37 patients who had received chemotherapy. The Rhodes Index of Nausea, Vomiting, and Retching (RINVR) was used, with multivariate data analysis through multiple regression.

Results: Among the 37 samples, the most common data findings were female sex (75.6%), age 41-65 years (78.4%), breast cancer type (43.2%), cancer stage 3-4 (29.7%), chemotherapy cycle 1-4 (54.1%), and mild CINV (70.27%). The relationship between the demographic profiles and CINV was significant, with a p-value of 0.000. The F-value was 37.561 and the R-squared value was 0.688. Meanwhile, the relationship between chemotherapy profiles, such as cancer type, cancer stage, and chemotherapy cycle, had an F-value of 42.081 and an R-squared value of 0.793.0.793.

Limitations: This study may have a limited sample size, which could affect the reliability and generalizability of the findings. Larger sample sizes would provide more robust and representative data.

Contributions: This study provides valuable insights into how various profiles of cancer patients (such as age, sex, type of cancer, and overall health) may influence the likelihood of experiencing chemotherapy-induced nausea and vomiting.

Keywords:
1. Cancer type
2. cancer stage
3. chemotherapy cycle
Authors:
1 . Ni Ketut Kardiyudiani
2 . Maryudella Afrida
3 . Novi Widyastuti Rahayu
4 . Sita Indriyani
5 . Bernadette D Quiambao
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How to Cite
Kardiyudiani, N. K., Afrida, M. ., Rahayu , N. W. ., Indriyani, S., & Quiambao, B. D. . (2024). Pengaruh Profil Pasien Kanker yang Mendapat Kemoterapi dengan Chemotherapy Induced Nausea and Vomiting (CINV) . Ners Akademika, 3(1), 15–22. https://doi.org/10.35912/nersakademika.v3i1.3905
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Vol. 3 No. 1 (2024): Desember
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  1. Andini, S., Siswandi, A., Anggunan, A., & Setiawati, O. R. (2022). Hubungan stadium kanker payudara dengan insomnia pada penderita kanker payudara yang sedang menjalani kemoterapi di RSUD Dr. H. Abdul Moeloek Provinsi Lampung. Jurnal Kesehatan Tambusai, 3(1), 271-279
  2. Dewi, S.U., Waluyo, A. and Maria, R. (2022) ‘Penerapan Akupresur Untuk Menurunkan Mual Muntah Akibat Kemoterapi Pada Pasien Kanker’, Jurnal Ilmiah Kesehatan Pencerah, 11(1), pp. 59–69.
  3. Dinkes Prop. Diy. (2019). Profil Kesehatan Propinsi Daerah Istimewa Yogyakarta. Yogyakarta. Dinkes Diy.
  4. Erdogan, G., & Mollaoglu, M. (2014).Effect On Symptom Of Structured Information Given To Patients Receiving Chemotherapy.European Journal Of Oncology Nursing, 18 (1), 78-84. Doi: 10.1016/J.Ejon.2013.07.006
  5. Fortenbaugh, C. and Rummel, M. (2004) ‘Chemotherapy safety.’, Clinical journal of oncology nursing, 8(4), pp. 424–425. Available at: https://doi.org/10.1188/04.cjon.424-425.
  6. Global Cancer Observatory. (2020). Estimated Number Of New Cases In 2020, Mexico, Both Sexes, All Ages. Word Health Organization, 983, 1.
  7. Gustini, G., Sukartini, T., & Krisnana, I. (2019). Nausea-Vomiting And Anorexia In Post-Chemotherapy Patients. Jurnal Penelitian Kesehatan" Suara Forikes"(Journal Of Health Research" Forikes Voice"), 10(3), 231-234.
  8. Hafsah, L. (2022). Gambaran Tingkat Kecemasan Pada Pasien Kanker Yang Menjalani Kemoterapi Di Rsud Dr. M. Yunus Bengkulu. Jurnal Vokasi Keperawatan (Jvk), 5(1), 21-28.
  9. Herrstedt, J., Lindberg, S. and Petersen, P.C. (2022) ‘Prevention of Chemotherapy-Induced Nausea and Vomiting in the Older Patient: Optimizing Outcomes’, Drugs and Aging, 39(1), pp. 1–21. Available at: https://doi.org/10.1007/s40266-021-00909-8.
  10. Hesketh, P. J., Kris, M. G., Basch, E., Bohlke, K., Barbour, S. Y., Clark-Snow, R. A., ... & Lyman, G. H. (2017). Antiemetics: American Society Of Clinical Oncology Clinical Practice Guideline Update. Journal Of Clinical Oncology, 35(28), 3240-3261.
  11. Juartika, W., Harmi, P.K. and Fatmadona, R. (2020) ‘Gambaran Skor INVR (Index of Nausea, Vomiting and Retching) pada CINV (Chemotherapy Induced Nausea and Vomiting) Kanker Payudara di RSUP M Djamil Padang’, Jurnal Kesehatan Andalas, 8(4), pp. 209–214. Available at: https://doi.org/10.25077/jka.v8i4.1142.
  12. Kemenkes Ri. (2020). Hasil Utama Riskesdas 2020. Pusat Data Dan Informasi Kemenkes Ri.
  13. Kusumawardani, Erwina Eka Yosita, Angélica Link, Viviane Aparecida Bussolaro, G. De N.J. Et Al. (2021) ‘Evaluasi Penatalaksanaan Mual Muntah Pasca Kemoterapi Pada Pasien Kanker Serviks Di Rumah Sakit Umum Pusat Dr. Kariadi Semarang Periode 2019’, Pesquisa Veterinaria Brasileira, 26(2), Pp. 173–180.
  14. Loprinzi, C., Bensinger, W. and Peterson, D. (2018) ‘Understanding and managing chemotherapy side effects’, pp. 4–7.
  15. Prasetyo, D.Y. and Suprayitno, E. (2019) ‘Faktor Kualitas Hidup Pasien Kanker’, Care:Jurnal Ilmiah Ilmu Kesehatan, 9(2), pp. 322–333.
  16. Pratiwi, S. R., Widianti, E., & Solehati, T. (2017). Gambaran Faktor-Faktor Yang Berhubungn Dengan Kecemasan Pasien Kanker Payudara Dalam Menjalani Kemoterapi. Jurnal Keperawatan Indonesia, 167-174.
  17. Prigerson, H.G. et al. (2015) ‘Chemotherapy use, performance status, and quality of life at the end of life’, JAMA Oncology, 1(6), pp. 778–784. Available at: https://doi.org/10.1001/jamaoncol.2015.2378.
  18. Siyoto, Sandu Dan Sodik, M. Ali. 2015. Dasar Metodologi Penelitian. Yogyakarta: Literasi Media Publishing.
  19. Sugiyono. (2016). Metode Penelitian Kuantitatif, Kualitatif Dan R&D. Bandung: Pt Alfabet.
  20. Syarif, H. (2016) ‘menurunkan mual muntah akibat kemoterapi pada pasien karsinoma nasofaring Accupressure Application In P 6 And ST 36 To Decrease Nausea And Vomit Of Chemotherapy Effect With Patient With Nasopharyng Carcinoma’, Idea Nursing Jurnal, II(3), pp. 199–107.
  21. Yildirim, d., baykal, d. And dedeo?lu demir, b. (2021) ‘The Attitudes of Cancer Patients with Nausea and Vomiting Symptoms to Complementary and Holistic Treatments: A Cross-Sectional Study’, Journal of Traditional Medical Complementary Therapies, 4(2), pp. 238–245. Available at: https://doi.org/10.5336/jtracom.2020-80681.